研究業績

<著書>

H. Suzuki, Y. Matano, T. Ogawa, N. Komatsu, T. Murafuji, T. Ikegami.
Organobismuth Chemistry
Elsevier Science, 2001

<総説>

Recent advance in the synthesis of optically active compounds bearing a chiral heteroatom center inthe group 13-16 elements.
Curr. Org. Chem. 2002, 6, 1469-1494.


Toshihiro Murafuji 「メタル化反応による置換アズレン類の簡便合成」(Convenient Synthesis of Substituted Azulenes Based on Metalation)
J. Synth. Org. Chem., Jpn., 2013, 71, 217-228.  有機合成化学協会 2013, 71, 217-228.

<最近の論文>

A. F. M. Mustafizur, Rahman T. Murafuji, T. Shibasaki, K. Suetake, K. Kurotobi, Y. Sugihara.
Characterization of azulenylphosphine derivatives. Unexpected debromination and its synthetic utility in the preparation of 2-substituted azulene.
Organometallics. 2007, 26, 2971-2977.

S. Hirakawa, J, Kawamata, Y. Suzuki, S. Tani, T. Murafuji, K, Kasatani, L. Antonov, K. Kamada, K. Ohta
Two-photon absorption properties of azulenyl compounds having a conjugated ketone backbone.
J. Phys. Chem. A. 2008, 112, 5198-5207.

T. Shibasaki, T. Ooishi, N. Yamanouchi, T. Murafuji, K. Kurotobi, Y. Sugihara.
A new efficient route to 2-substituted azulenes based on sulfonyl group directed lithiation.
J. Org. Chem. 2008, 73, 7971-7977.

M. Fujinaga, K. Suetake, K. Gyoji, T. Murafuji, K. Kurotobi, Y. Sugihara.
An easy access to 2-substituted azulenes from azulene-2-boronic acid pinacol ester.
Synthesis. 2008, 3745-3748.

M. Fujinaga, T. Murafuji, K. Kurotobi, Y. Sugihara.
Polyborylation of azulenes.
Tetrahedron. 2009, 65, 7115-7121.

J. Oshita, S. Matsui, R. Yamamoto, T. Mizumo, Y. Ooyama, Y. Harima, T. Murafuji, K. Tao, Y. Kuramochi, T. Kaikoh, H. Higashiyama.Synthesis of dithienobismoles as novel phosphorescence materials.
Organometallics. 2010, 29, 3239-3241.

H. Fujii, K. Nagamatus, T. Gunji, T. Murafuji, N. Abe.
The reaction of [(1-azaazulen-2-yl)imino]phosphorane with arylaldehydes: Formation of bis[(1-azaazulen-2-yl)amino]arylmethanes.Heterocycles, 2010, 81, 2625-2633.

T. Murafuji, Y. Fujiwara, D. Yoshimatsu, K. Migita, I. Miyakawa, Y. Mikata.
Antifungal bismuth heterocycles based on diphenyl sulfone scaffold.
Eur. J. Med. Chem. 2011, 46, 519-525.

J. Chen, T. Murafuji, R. Tsunashima.
Insertion of benzyne into a Bi-S Bond: A new synthetic route to ortho-functionalized bismuthanes and its application to the synthesis of dibenzothiophene.
Organometallics. 2011, 30, 4532-4538.

Y. Matano, Y. Kon, A. Saito, Y. Kimura, T. Murafuji, H. Imahori.
Divergent synthesis of 2,5-diarylphospholes based on cross-coupling reactions: substituent effects on the optical and redox properties of benzene-phosphole-benzene p-systems.
Chem. Lett. 2011, 40, 919-921.

E. Yoshioka, H. Fujii, T. Murafuji, R. Ikeda, T. Konakahara, T. Gunji, N. Abe.
Synthesis of 12,12a-dihydro-7,12a-diazacyclohepta[cd]benz[g]azulen-12-one(cyclohepta-[mn]pyrrolo[2,1-c][1,4]-benzodiazepin-12-one) and evaluation of cytotoxic activity against HeLa S3 cells.
Heterocycles, 2011, 83, 1409-1415.


E. Yoshioka, K. Koizumi, K. Nakashima, H. Fujii, T. Murafuji, T. Gunji, N.Abe.
Synthesis and Complexation of Bis(1-azaazulen-2-yl)amines and Bis(1-azaazulen-2-yl)Sulfides
activity against HeLa S3 cells.
Heterocycles, 2012, 85, 1683-1695.


A. Kamimura, Shingo Ishikawa, F. Noguchi, T. Moriyama, M. So, T. Murafuji, H. Uno.
Unexpected formation of stannolanes and trigonal bipyramidal tin complexes by radical cyclization reaction
Chem. comm. 2012, 48, 6592-6594


M. Nakatani, H. Fujii, T. Murafuji, T. Gunji, R.Ikeda. T.Kanahara, N. Abe.
Synthesis of Benzotropone-Annulated 1-Azaazulenes and Related Compounds by Suzuki-Miyaura Coupling /
Aldol Condensation Cascade Reaction and Evaluations of Their Cytotoxic Activity against HeLa S3 Cells

Heterocycles, 2012, 84, 461-472.


T. Murafuji, K. Kitagawa, D. Yoshimatsu, K. Kondo, K. Ishiguro, R. Tsunashima, I. Miyakawa, Y. Mikata.
Heterocyclic bismuth carboxylates based on a diphenyl sulfone scaffold: Synthesis and antifungal activity against Saccharomyces cerevisiae
Eur. J. Med. Chem. , 2013, 63, 531-535.




<特許出願>

新規非共鳴二光子吸収化合物
川俣 純、平川祥一郎、村藤俊宏、笠谷和男、丸本卓哉
特願2006-162583

薄膜及びこれらに用いられる化合物
大下浄治、村藤俊宏、倉持悠輔、東村秀之
特願2010-53389

アズレン又はアズレン誘導体の4,4,5,5-テトラメチル-1,3,2-ジオキサボロラン誘導体の製造法
藤永雅之、村藤俊宏、檜山久美子
特願2010-212053

1-置換アズレン誘導体の製造法
岡畑 甫、村藤俊宏
特願2011-006300

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