英文論文(2004年~)



2016年

K. Yakabe, A. Murakami, T. Kajimura, Y. Nishimoto, K. Sueoka, S. Sato, S. Nawata and N. Sugino. Functional significance of transgelin-2 in uterine cervical squamous cell carcinoma. The Journal of Obstetrics and Gynaecology Research.

M.Okada,L.Lee,R.Maekawa,S.Sato,T.Kajimura,M.Shinagawa,I.Tamura,T.Taketani,H.Asada,H.Tamura, N.Sugino. Epigenetic Changes of the Cyp11a1 Promoter Region in Granulosa Cells Undergoing Luteinization During Ovulation in Female Rats. Endocrinology. doi: 10.1210/en.2016-1264. 157(9): 3344-3354

S.Sato, R.Maekawa, Y.Yamagata, I.Tamura, L.Lee, M.Okada, K.Jozaki, H.Asada, H.Tamura, N.Sugino. Identification of uterine leiomyoma-specific marker genes based on DNA methylation and their clinical application. Scientific Reports. 6:30652 DOI: 10.1038/srep30652

M. Suzuki1 , R. Maekawa, N. E. Patterson, D. M. Reynolds, B. R. Calder, S. E. Reznik, H. J. Heo, F. Hughes Einstein J. M. Greally. Amnion as a surrogate tissue reporter of the effects of maternal preeclampsia on the fetus. Clinical Epigenetics. DOI 10.1186/s13148-016-0234-1 8(67): 1-13

R.Maekawa, S.Sato, M.Okada, L.Lee, I.Tamura, K.Jozaki, T.Kajimura, H.Asada, Y.Yamagata, H.Tamura, S.Yamamoto, N.Sugino. Tissue-specific expression of estrogen receptor 1 is regulated by DNA methylation in a T-DMR. Mol Endocrinol. 30(3): 335-347


2015年

R Maekawa, S Sato, M Okada, L Lee, I Tamura, K Jozaki, T Kajimura, H Asada, Y Yamagata, H Tamura, S Yamamoto, N Sugino. (2015) Tissue-specific expression of estrogen receptor 1 is regulated by DNA methylation in a T-DMR. Mol Endocrinol. 18: 1058

K Yakabe, A Murakami, Y Nishimoto, T Kajimura, K Sueoka, N Sugino (2015) Clinical implications of human leukocyte antigen class I expression in endometrial cancer MOLECULAR AND CLINICAL ONCOLOGY DOI: 10.3892/mco.2015.636 3: 1285-1290

Y Yamagata, E Takaki, M Shinagawa, M Okada, K Jozaki, L Lee, S Sato, R Maekawa, T Taketani, H Asada, H Tamura, A Nakai, N Sugino (2015) Retinoic acid has the potential to suppress endometriosis development Journal of Ovarian Research 8 (1): 49

M Tanabe, H Tamura, T Taketani, M Okada, L Lee, I Tamura, R Maekawa, H Asada, Y Yamagata, N Sugino (2015) Melatonin protects the integrity of granulosa cells by reducing oxidative stress in nuclei, mitochondria, and plasma membranes in mice. J Reprod Dev. 61 (1): 35-41

2014年

H Tamura, A Takasaki, Y Nakamura, F Numa, N Sugino (2014) A pilot study to search possible mechanisms of ultralong gonadotropin-releasing hormone agonist therapy in IVF-ET patients with endometriosis. J Ovarian Res. [Epub ahead of print] 7 (1)

I Tamura, Y Ohkawa, T Sato, M Suyama, K Jozaki, M Okada, L Lee, R Maekawa, H Asada, S Sato, Y Yamagata, H Tamura, N Sugino (2014) Genome-wide analysis of histone modifications in human endometrial stromal cells. Mol Endocrinol. me20141117. [Epub ahead of print] 28 (10): 1656-1669

F Kizuka-Shibuya, N Tokuda, K Takagi, Y Adachi, L Lee, I Tamura, R Maekawa, H Tamura, T Suzuki, Y Owada, N Sugino (2014) Locally existing endothelial cells and pericytes in ovarian stroma, but not bone marrow-derived vascular progenitor cells, play a central role in neovascularization during follicular development in mice. J Ovarian Res. 7 (1)

S Sato, R Maekawa, Y Yamagata, H Asada, I Tamura, L Lee, M Okada, H Tamura, N Sugino (2014) Potential Mechanisms of Aberrant DNA Hypomethylation on the X Chromosome in Uterine Leiomyomas. J Reprod Dev. 60 (1): 47-245

I Tamura, S Sato, M Okada, M Tanabe, L Lee, R Maekawa, H Asada, Y Yamagata, H Tamura, N Sugino (2014) Importance of C/EBPβ binding and histone acetylation status in the promoter regions for induction of IGFBP-1, PRL, and Mn-SOD by cAMP in human endometrial stromal cells. Endocrinology.doi: 10.1210/en.2013-1569. Epub 2013 Dec 20 155 (1): 275-286


2013年

Maekawa R, Sato S, YamagataY, Asada H, Tamura I, Lee L, Okada M, Tamura H, Takaki E, Nakai A, Sugino N (2013) Genome-wide DNA methylation analysis reveals a potential mechanism for the pathogenesis and development of uterine leiomyomas. PLOS ONE 8 (6): e66632

Tamura H, Takasaki A, Taketani T, Tanabe M, Kizuka F, Lee L, Tamura I, Maekawa R, Asada H, Yamagata Y, Sugino N (2013) Melatonin as a free radical scavenger in the ovarian follicle. Endocr J 60: 1-13.

Lee L, Asada H, Kizuka F, Tamura I, Maekawa R, Taketani T, Sato S, Yamagata Y, Tamura H, Sugino N (2013) Changes in histone modification and DNA methylation of the StAR and Cyp19a1 promoter regions in granulosa cells undergoing luteinization during ovulation in female rats. Endocrinology 154: 458-470.


2012年

Tamura H, Takasaki A, Taketani T, Tanabe M, Kizuka F, Lee L, Tamura I, Maekawa R, Asada H, Yamagata Y, Sugino N (2012) Melatonin protects oocytes from reactive oxygen species. Bull Yamaguchi Med Sch 59: 43-51.

Yoshioka S, King ML, Ran S, Okuda H, MacLean JA, Sugino N, Brard L, Watabe K, Hayashi K (2012) WNT7A regulates tumor growth and progression in ovarian cancer through the WNT/β-catenin pathway. Mol Cancer Res 10: 469-482.

Tamura I, Asada H, Maekawa R, Tanabe M, Lee L, Taketani T, Yamagata Y, Tamura H, Sugino N (2012) Induction of IGFBP-1 expression by cAMP is associated with histone acetylation status of the promoter region in human endometrial stromal cells. Endocrinology153: 5612-5621.

Al-Gubory KH, Garrel C, FaureP, Sugino N (2012) Roles of antioxidant enzymes in corpus luteum rescue from reactive oxygen species-induced oxidative stress. Reprod BioMed Online 25: 551-560.

Kizuka F, Tokuda N, Takagi K, Adachi Y, Lee L, Tamura I, Maekawa R, Taketani T, Tamura H, Suzuki T, Owada Y, Sugino N (2012) Involvement of bone marrow-derived vascular progenitor cells in neovascularization during formation of the corpus luteum in mice. Biol Reprod 87 (3):55: 1-7.

Murakami A, Yakabe K, Yoshidomi K, Sueoka K, Nawata S, Yokoyama Y, Tsuchida S, Fahd Al-Mulla, Sugino N (2012) Decreased carbonyl reductase 1 expression promotes malignant behaviours by induction of epithelial mesenchymal transition and its clinical significance. Cancer Lett 323: 69-76.

Murakami A, Yoshidomi K, Sugino N (2012) Involvement of squamous cell carcinoma antigen in invasion and metastasis of squamous cell carcinoma of uterine cervix. Squamous cell carcinoma, edited by Xiaoming Li, InTech open access book, ISBN 978-953-0024-9; 153-160.

Tamura H, Takasaki A, Taketani T, Tanabe M, Kizuka F, Lee L, Tamura I, Maekawa R, Asada H, Yamagata Y, Sugino N (2012) The role of melatonin as an antioxidant in the follicle. J Ovarian Res 5:5


2011年

Maekawa R, Yagi S, Ohgane J, Yamagata Y, Asada H, Tamura I, Sugino N, Shiota K (2011) Disease-dependent differentially methylated regions (D-DMRs) of DNA are enriched on the X chromosome in uterine leiomyoma. J Reprod Dev 57: 604-619.

Murakami A, Fukushima C, Yoshidomi K, Sueoka K, Nawata S, Yokoyama Y, Tsuchida S, Ismail E, Al-Mulla F, Sugino N (2011) Suppression of carbonyl reductase expression enhances malignant behaviour in uterine cervical squamous cell carcinoma: Carbonyl reductase predicts prognosis and lymph node metastasis. Cancer lett 311: 77-84.

Nawata S, Shi HY, Sugino N, Zhang M (2011) Evidence of post-translational modification of the tumor suppressor maspin under oxidative stress. Int J Mol Med 27: 249-254.

Iwasaki Y, Goto M, Mochizuki K, Terayama E, Ito R, Saito K, Sugino N, Makino T, Nakazawa H (2011) Development and validation of a hydrophilic interaction chromatography-tandem mass spectrometry for quantification of nicotine and its metabolites in human maternal and cord sera. Biomed Chromatogr 25: 503-510.

Tamura I, Taketani T, Lee L, Kizuka F, Taniguchi K, Maekawa R, Asada H, Tamura H, Sugino N (2011) Differential effects of progesterone on COX-2 and Mn-SOD expressions are associated with histone acetylation status of the promoter region in human endometrial stromal cells. J Clin Endocrinol Metab 96: E1073-E1082

Arai Y, Ohgane J, Yagi S, Ito R, Iwasaki Y, Saito K, Akutsu K, Takatori S, Ishii R, Hayashi R, Izumi S, Sugino N, Kondo F, Horie M, Nakazawa H, Makino T, Shiota K (2011) Epigenetic assessment of environmental chemicals detected in maternal peripheral and cord blood samples. J Reprod Dev 57: 507-517.

Taketani T, Tamura H, Takasaki A, Lee L, Kizuka F, Tamura I, Taniguchi K, Maekawa R, Asada H, Shimamura K, Reiter RJ, Sugino N (2011) Protective role of melatonin in progesterone production by human luteal cells. J Pineal Res 51: 207-213.

Fukushima C, Murakami A, Yoshitomi K, Sueoka K, Nawata S, Nakamura K, Sugino N (2011) Comparative proteomic profiling in squamous cell carcinoma of the uterine cervix. Proteomics Clin Appl 5: 133-140.

Murata S, Nakata M, Sumie M, Sugino N (2011) The Doppler cerebroplacental ratio predicts non-reassuring fetal status in intrauterine growth restricted fetuses at term. J Obstet Gynaecol Res 37: 1433-1437

Takasaki A, Tamura I, Kizuka F, Lee L, Maekawa R, Asada H, Taketani T, Tamura H, Shimamura K, Morioka H, Sugino N (2011) Luteal blood flow in patients undergoing GnRH agonist long protocol. J Ovarian Res 4:2 (doi;10.1186/1757-2215-4-2).


2010年

Taniguchi K, Matsuoka A, Kizuka F, Lee L, Tamura I, Maekawa R, Asada H, Taketani T, Tamura H, Sugino N (2010) Prostaglandin F2α (PGF2α) stimulates PTGS2 expression and PGF2α synthesis through NFKB activation via reactive oxygen species in the corpus luteum of pseudopregnant rats. Reproduction 140: 885-892.

Matsuoka A, Kizuka F, Lee L, Tamura I, Taniguchi K, Asada H, Taketani T, Tamura H, Sugino N (2010) Progesterone increases manganese superoxide dismutase expression via a cAMP-dependent signaling mediated by non-canonical Wnt5a pathway in human endometrial stromal cells. J Clin Endocrinol Metab 95: E291-E299.

Murakami A, Fukushima C, Yoshitomi K, Sueoka K, Nawata S, Fujimoto M, Nakamura K, Sugino N (2010) Tumor-related protein, the aquamous cell carcinoma antigen binds to the intracellular protein carbonyl reductase. Int J Oncol 36: 1395-1400.

Kawauchi S, Nawata H, Yamagata Y, Yaegashi H, Fukunaga M, Moriya T, Furuya T, Sugino N, Sasaki K (2010) Chromosomal imbalances detected by comparative genomic hybridization provide evidence that HMB-45-negative uterine angiomyolipomas belong to the PEComa family. Histopathology 56; 968-982.

Takasaki A, Tamura H, Miwa I, Taketani T, Shimamura K, Sugino N (2010) Endometrial growth and uterine blood flow: a pilot study for improving endometrial thickness in the patients with a thin endometrium. Fertil Steril 93: 1851-1858.


2009年

Sumie M, Nakata M, Murata S, Miwa I, Sugino N (2009) Two cases of reversal of twin-twin transfusion syndrome diagnosed by measuring hourly fetal urine production. J Obstet Gynaecol Res 35: 983-986.

Nakata M, Murakoshi T, Sago H, Ishii K, Takahashi Y, Hayashi S, Murata S, Miwa I, Sumie M, Sugino N (2009) Modified sequential laser photocoagulation of placental communicating vessels for twin-twin transfusion syndrome to prevent fetal demise of the donor twin. J Obstet Gynaecol Res 35: 640-647.

Murata S, Nakata M, Sumie M, Matsubara M, Sugino N (2009) Prenatal diagnosis of pentalogy of cantrell with craniorachisis by three-dimensional ultrasonography in the first trimester. Taiwanese J Obstet Gynecol 48: 317-318.

Tamura H, Nakamura Y, Korkmaz A, Manchester LC, Tan DX, Sugino N, Reiter RJ (2009) Melatonin and the ovary; physiological and pathophysiological implications. Fertil Steril 92: 328-343.

Fukunaga S, Ichiyama T, Maeda S, Okuda M, Nakata M, Sugino N, Furukawa S. (2009) MMP-9 and TIMP-1 in the cord blood of premature infants developing BPD. Pediatric Pulmonology 44: 267-272.

Takasaki A, Tamura H, Taniguchi K, Asada H, Taketani T, Matsuoka A, Yamagata Y, Shimamura K, Morioka H, Sugino N (2009) Luteal blood flow and luteal function. J Ovarian Res 2: 1 (doi:10.1186/1757-2215-2-1).

Yamagata Y, Asada H, Tamura I, Lee L, Maekawa R, Taniguchi K, Taketani T, Matsuoka A, Tamura H, Sugino N (2009) DNA methyltransferase expression in the human endometrium: down-regulation by progesterone and estrogen. Hum Reprod 24: 1126-1132.

Yamagata Y, Maekawa R, Asada H, Taketani T, Tamura I, Tamura H, Ohgane J, Hattori N, Shiota K, Sugino N (2009) Aberrant DNA methylation status in human uterine leiomyoma. Mol Hum Reprod 15: 259-267.

Miwa I, Tamura H, Takasaki A, Yamagata Y, Shimamura K, Sugino N (2009) Pathophysiological features of thin endometrium. Fertil Steril 91: 998-1004.

Yamagata Y, Kawaguchi S, Tamura H, Murakami A, Sasaki K, Sugino N (2009) A case of HMB45-negative perivascular epithelioid cell tumor (PEComa) of the uterine corpus: A possible diagnostic application of molecular-cytogenetic analysis. Eur J Gynaec Oncol 30: 216-219.


2008年

Nakata M, Sumie M, Murata S, Miwa I, Matsubara M, Sumie M, Sugino N (2008) Fetoscopic lazer photocoagulation of placental communicating vessels for twin reversed-arterial perfusion sequence. J Obstet Gynaecol Res 34: 649-652.

Tamura H, Takasaki A, Taniguchi K, Matsuoka A, Shimamura K, Sugino N (2008) Changes in blood flow impedance of the human corpus luteum throughout the luteal phase and during early pregnancy. Fertil Steril 90: 2334-2339.

Nakamura Y, Maekawa R, Yamagata Y, Tamura H, Sugino N (2008) A novel mutation in exon8 of the follicle-stimulating hormone receptor in a woman with primary amenorrhea. Gynecol Endocrinol 24: 708-712.

Asada H, Yamagata Y, Taketani T, Matsuoka A, Tamura H, Hattori N, Ohgane J, Hattori N, Shiota K, Sugino N (2008) Potential link between estrogen receptor-α gene hypomethylation and uterine fibroid formation. Mol Hum Reprod14: 539-545.

Matsubara M, Nakata M, Murata S, Miwa I, Sumie M, Sugino N (2008) Resolution of mirror syndrome after successful fetoscopic laser photocoagulation of communicating placental vessels in severe twin-twin transfusion syndrome. Prenat Diagn 10.1002/pd 2128.

Yamagata Y, Maekawa R, Asada H, Tamura I, Taniguchi K, Taketani T, Miwa I, Matsuoka A, Tamura H, Sugino N (2008) Primary amenorrhea in a 18-year-old Japanese female with sensorineural hearing loss and anosmia: a new syndrome? Endocr J 55: 545-547.

Tamura H, Nakamura Y, Terron MP, Flores LJ, Manchester LC, Tan DX, Sugino N, Reiter RJ (2008) Melatonin and pregnancy in the human. Reprod Toxicol 25: 291-303.

Tamura H, Nakamura Y, Narimatsu A, Yamagata Y, Takasaki A, Reiter RJ, Sugino N (2008) Melatonin treatment in peri- and postmenopausal women elevates serum high-dendity lipoprotein cholesterol levels without influencing total cholesterol levels. J Pineal Res 45: 101-105, 2008.

Taketani T, Yamagata Y, Takasaki A, Matsuoka A, Tamura H, Sugino N (2008) Effects of growth hormone and insulin-like growth factor I on progesterone production in human luteinized granulose cells. Fertil Steril 90: 744-748.

Tamura H, Takayama H, Nakamura Y, Reiter RJ, Sugino N (2008) Fetal / placental regulation of maternal melatonin in rats. J Pineal Res 44: 335-340.

Sugino N, Matsuoka A, Taniguchi K, Tamura H (2008) Angiogenesis in the human corpus luteum. Reprod Med Biol 7: 91-103.

Sugino N, Miwa I, Tamura H, Takasaki A, Shimamura K (2008) Characterization of “thin” endometrium and treatment with vitamin E. In: Translational research in uterine biology. Maruo T, Mardon H, and Stewart C, eds. Elsevier; 2008: 111-118.

Murakami A, Nakagawa T, Fukushima C, Torii M, Sueoka K, Nawata S, Takeda O, Ishikawa H, Sugino N (2008) Relationship between decreased expression of squamous cell carcinoma antigen 2 and E-cadherin in primary cervical cancer lesions and lymph node metastasis. Onco Reports 19: 99-104.

Tamura H, Miwa I, Taniguchi K, Maekawa R, Asada H, Taketani T, Matsuoka A, Yamagata Y, Ishikawa H, Sugino N (2008) Different changes in resistance index between uterine artery and uterine radial artery during pregnancy. Hum Reprod 23: 285-289.

Tamura H , Takasaki A, Miwa I, Taniguchi K, Maekawa R, Asada H, Taketani T, Matsuoka A, Yamagata Y, Shimamura K, Morioka H, Ishikawa H, Reiter RJ, Sugino N (2008) Oxidative stress impairs oocyte quality and melatonin protects oocytes from free radical damage and improves fertilization rate. J Pineal Res 44: 280-287.


2007年

Sugino N, Okuda K (2007) Species-related differences in the mechanism of apoptosis during structural luteolysis. J Reprod Dev 53: 977-986.

Nakagawa T, Murakami A, Torii M, Nawata S, Takeda O, Sugino N (2007) E-cadherin increases squamous cell carcinoma antigen expression through phosphatidylinositol-3 kinase-Akt pathway in squamous cell carcinoma cell lines. Onco Reports 18: 175-179.

Sugino N (2007) The role of oxygen radical-mediated signaling pathways in endometrial function. Placenta 28, Suppl A, Trophoblast Res 21: S133-S136.

Sugino N, Takiguchi S, Umekawa T, Heazell A, Caniggia I (2007) Oxidative stress and pregnancy outcome: A wokshop report. Placenta 28, Suppl A, Trophoblast Res 21: S48-S50.

Nakata M, Sumie M, Murata S, Miwa I, Kusaka E, Sugino N (2007) A case of monochorionic twin pregnancy complicated with intrauterine single fetal death with successful treatment of intrauterine blood transfusion in the surviving fetus. Fetal Diagn Ther 22: 7-9.


2006年

Murakami A, Nakagawa T, Kaneko M, Nawata S, Takeda O, Kato H, Sugino N (2006) Suppression of SCC antigen promotes cancer cell invasion and migration through the decrease in E-cadherin expression. Int J Oncol 29: 1231-1235.

Sugino N (2006) Roles of reactive oxygen species in the corpus luteum. Animal Science Journal 77: 556-565.

Nawata S, Murakami A, Torii M, Nakagawa T, Sueoka K, Takeda O, Suminami Y, Nakamura K, Kato H, Sugino N (2006) Different expression patterns of intact forms of squamous cell carcinoma antigens between normal and malignant cervical squamous : nondeneraturing polyacrylamide gel electrophoretic analysis. Onco Reports 16: 399-404.

Matsuoka-Sakata A, Tamura H, Asada H, Miwa I, Taketani T, Yamagata Y, Sugino N (2006) Changes in vascular leakage and expression of angiopoietins in the corpus luteum during pregnancy in rats. Reproduction 131: 351-360.


2005年

Sugino N, Suzuki T, Sakata A, Miwa I, Asada H, Taketani T, Yamagata Y, Tamura H (2005) Angiogenesis in the human corpus luteum: Changes in expression of angiopoietins in the corpus luteum throughout the menstrual cycle and in early pregnancy. J Clin Endocrinol Metab 90: 6141-6148.

Sugino N (2005) Roles of eactive oxygen species and superoxide dismutase in the corpus luteum and endometrium. Trends in Reprod Biol 1: 1-14.

Nakata M, Fujiwara M, Ishikawa Y, Sumie M, Hasegawa K, Miwa I, Kusaka E, Sase M, Sugino N (2005) Prenatal diagnosis and management for a large fetal cardiac tumor complicated with hydrops fetalis. J Obstet Gynecol Res 31: 476-479.

Sase M, Miwa I, Sumie M, Nakata M, Sugino N, Okada K, Osa A, Miike H, Ross MG (2005) Gastric emptying cycles in the human fetus. Am J Obstet Gynecol 193: 1000-1004.

Sase M, Miwa I, Sumie M, Nakata M, Sugino N, Ross MG (2005) Ontogeny of gastric emptying patterns in human fetus. J Maternal-Fetal and Neonatal Med 17: 213-217.

Sase M, Haegawa K, Honda R, Sumie M, Nakata M, Sugino N, Furukawa S (2005) Ultrasonographic findings of facial dysmorphism in Wolf-Hirschhorn syndrome. Am J Perinatol 22: 99-102.

Sueoka K, Nawata S, Nakagawa T, Murakami A, Takeda O, Suminami Y, Kato H, Sugino N (2005) Tumor-associated serpin, squamous cell carcinoma antigen stimulates matrix metalloproteinase-9 production in cervical squamous cell carcinoma cell lines. Int J Oncol 27: 1345-1353.

Suminami Y, Kishi F, Nawata S, Murakami A, Sakaguchi Y, Sueoka K, Numa F, Sugino N, Kato H (2005) Promoter analyses of SCC antigen genes. Biochim Biophys Acta 1727: 208-212.

Sugino N (2005) Reactive oxygen species in ovarian physiology. Reprod Med Biol 4: 31-44.


2004年

Sugino N, Karube-Harada A, Taketani T, Sakata A, Nakamura Y (2004) Withdrawal of ovarian steroids stimulates prostaglandin F2a production through nuclear factor-kB activation via oxygen radicals in human endometrial stromal cells: potential relevance to menstruation. J Reprod Dev 50: 215-225.

Takiguchi S, Sugino N, Esato K, Karube-Harada A, Sakata A, Nakamura Y, Ishikawa H, Kato H (2004) Differential regulation of apoptosis in the corpus luteum of pregnancy and newly formed corpus luteum after parturition in rats. Biol Reprod 70: 313-318.

Hirakawa H, Nawata S, Sueoka K, Murakami A, Takeda O, Numa F, Kato H, Sugino N (2004) Regulation of squamous cell carcinoma antigen production by E-cadherin mediated cell-cell adhesion in squamous cell carcinoma cell line. Oncology Reports 11: 415-419.