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研究業績

論文発表（2016年以降）

原著論文

1. Kohyanagi N, Kitamura N, Ikeda S, Shibutani S, Sato K, and Ohama T.
   PP2A inhibitor SET promotes mTORC1 and Bmi1 signaling through Akt activation and maintains the colony-formation ability of cancer cells.
   J Biol Chem. 2024; 300(1); 105584.
2. Ohkubo K, Shibutani S, Iwata H.
   AMP-activated protein kinase (AMPK) suppresses Ibaraki virus propagation.
   Virology. 2024; 590: 109943.
3. Hanaki S, Habara M, Sato Y, Tomiyasu H, Miki Y, Shibutani S, Shimada M.
   Dephosphorylation of NFAT by Calcineurin inhibits Skp2-mediated degradation.
   J Biochem. 2023
4. Egusa K, Shibutani S, Iwata H.
   IgG and insulin enhance endocytosis in THP-1 cells via activation of phosphatidylinositol 3-kinase (PI3K).
   Biochem Biophys Res Commun. 2023; 679: 160-166.
5. Koshiishi T, Shibutani S, Chuma T, Iwata H.
   Measurement of serum procalcitonin concentrations in calves with bovine respiratory disease.
   Jpn J Vet Res. 2023; 71(2): 65-71.
6. Suemura M, Miyata H, Kawamura R, Takahashi S, Igase M, Mizuno T, Ohama T, Shibutani S, Iwata H.
   Cancer-specific apoptosis induction in canine lymphoma cell lines by the endocytosis inhibitor dynasore.
   J Vet Med Sci. 2023; 85(8): 820-827.
7. Murokawa H, Egusa K, Shibutani S, Iwata H.
   Mechanistic/mammalian target of rapamycin complex 1 (mTORC1) signaling is involved in phagocytosis activation during THP-1 cell differentiation.
   J Vet Med Sci. 2023; 85(7): 772-780.
8. Shibutani S, Endo M, Mizukami K, Hosoi E, Sakai Y, Taniguchi M, Harada H, Momozawa Y, Iwata H.
   Development of a high-throughput screening method for the detection of 188 pathogenic variants and its application in Mishima cattle.
   Anim Genet. 2023; 54(3): 416-417.
9. Ando S, Sakurai M, Shibutani S, Kimura N, Shimozawa N, Yasutomi Y, Yabe R, Ohama T, Sato K.
   Age-related alterations in protein phosphatase 2A methylation levels in brains of cynomolgus monkeys: a pilot study.
   J Biochem. 2023; 173(6): 435-445
10. Suemura M, Shibutani S, Iwata H.
    The endocytosis inhibitor dynasore induces a DNA damage response pathway that can be manipulated for enhanced apoptosis.
    Biochem Biophys Res Commun. 2023; 645: 1-9.
11. Masaki T, Habara M, Shibutani S, Hanaki S, Sato Y, Tomiyasu H, Shimada M.
    Dephosphorylation of the EGFR protein by calcineurin at serine 1046/1047 enhances its stability.
    Biochem Biophys Res Commun. 2023; 641: 84-92.
12. Takahashi S, Shibutani S, Iwata H.
    Nuclear-targeted 4E-BP1 is dephosphorylated, induces nuclear translocation of eIF4E, and alters mRNA translation.
    Exp Cell Res. 2022; 418(1): 113246.
13. Maeda Y, Shibutani S, Iwata H.
    Partial glycosylation of the Ibaraki virus NS3 protein is sufficient to support virus propagation.
    Virology. 2021; 563: 44-49.
14. Maeda Y., Shibutani S, Onishi K, Iwata H.
    Ibaraki virus enters host cells by macropinocytosis.
    Virus Res. 2021; 302: 198492.
15. Fujiwara N, Shibutani S, Ohama T, Sato K.
    Protein phosphatase 6 dissociates the Beclin 1/Vps34 complex and inhibits autophagy.
    Biochem Biophys Res Commun. 2021; 552: 191-195.
16. Goto N, Shibutani S, Miura N, Watanabe R, Iwata H.
    Thapsigargin suppresses alpha 1-acid glycoprotein secretion independently of N-glycosylation and ER stress.
    Biochem Biophys Res Commun. 2021; 552: 30-36.
17. Fujiwara N, Shibutani S, Sakai Y, Watanabe T, Kitabayashi I, Oshima H, Oshima M, Hoshida H, Akada R, Usui T, Ohama T, Sato K.
    Autophagy regulates levels of tumor suppressor enzyme protein phosphatase 6.
    Cancer Sci. 2020; 111(12): 4371-4380.
18. Maeda Y, Takeyoshi M, Chuma T, Iwata H.
    α-Sens: The improved ARE-Nrf2-based sensitization screening assay using normalized transcriptional activity
    Toxicology. 2020; 439: 152476.
19. Igase M, Fujiki N, Shibutani S, Sakai H, Noguchi S, Nemoto Y, Mizuno T.
    Tenovin-6 induces the SIRT-independent cell growth suppression and blocks autophagy flux in canine hemangiosarcoma cell lines.
    Exp Cell Res. 2020; 388(1): 111810.
20. Igase M, Shibutani S, Kurogouchi Y, Fujiki N, Hwang CC, Coffey M, Noguchi S, Nemoto Y, Mizuno T.
    Combination Therapy with Reovirus and ATM Inhibitor Enhances Cell Death and Virus Replication in Canine Melanoma.
    Mol Ther Oncolytics. 2019; 15: 49-59
21. Hirosaki H, Maeda Y, Shimojima M, Maeda K, Iwata H, Takeyoshi M.
    Effects of Soluble Tumor Necrosis Factor (TNF) on Antibody-Dependent Cellular Cytotoxicity of Therapeutic anti-TNF-α Antibody.
    Immunol Invest. 2019; 48(5): 441-450.
22. Tsuruta Y, Shibutani S, Watanabe R, Iwata H.
    Apoptosis induced by Ibaraki virus does not affect virus replication and cell death in hamster lung HmLu-1 cells.
    Journal of Veterinary Medical Science. 2019; 81(2): 197-203
23. Onishi K, Shibutani S, Goto N, Maeda Y, Iwata H.
    Amino acid starvation accelerates replication of Ibaraki virus.
    Virus Research. 2019; 15(260): 94-101
24. Shibutani S, Okazaki H, Iwata H.
    Dynamin-dependent amino acid endocytosis activates mechanistic target of rapamycin complex 1 (mTORC1).
    Journal of Biological Chemistry. 2017; 292(44): 18052-18061
25. Noguchi S, Shibutani S, Fukushima K , Mori T, Igase M, Mizuno T.
    Bosutinib, an SRC inhibitor, induces caspase-independent cell death associated with permeabilization of lysosomal membranes in melanoma cells.
    Veterinary and Comparative Oncology. 2017 doi: 10.1111/vco.12312
26. Tsuruta Y, Shibutani ST, Watanabe R, Iwata H.
    The requirement of environmental acidification for Ibaraki virus infection to host cells.
    Journal of Veterinary Medical Science. 2016; 78(1): 153-156.
27. Urata M, Watanabe R, Iwata H.
    The effect of glycosylation on cytotoxicity of Ibaraki virus nonstructural protein NS3.
    Journal of Veterinary Medical Science. 2016; 77(12):1611-1616.

総説論文

1. Klionsky DJ et al. (including Shibutani S)
   Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).
   Autophagy. 2016; 12(1): 1-222.

論文発表（2015年以前、岩田教授）

原著論文

1. Kato H, Gomez EA, Fujita M, Ishimaru Y, Uezato H, Mimori T, Iwata H, Hashiguchi Y.
   Ayadualin, a novel RGD peptide with dual antihemostatic activities from the sand fly Lutzomyia ayacuchensis, a vector of Andean-type cutaneous leishmaniasis.
   Biochimie. 2015 May;112:49-56.
2. Urata M, Watanabe R, Iwata H.
   The host specific NS3 glycosylation pattern reflects the virulence of Ibaraki virus in different hosts.
   Virus Res. 2014 Mar 6;181:6-10.
3. Kameyama M, Chuma T, Yabata J, Tominaga K, Iwata H, Okamoto K.
   Prevalence and epidemiological relationship of CMY-2 AmpC β-lactamase and CTX-M extended-spectrum β-lactamase-producing Escherichia coli isolates from broiler farms in Japan.
   J Vet Med Sci. 2013;75(8):1009-15.
4. Yamamoto K, Cáceres AG, Gomez EA, Mimori T, Iwata H, Korenaga M, Sakurai T, Katakura K, Hashiguchi Y, Kato H.
   Genetic diversity of the mitochondrial cytochrome b gene in Lutzomyia spp., with special reference to Lutzomyia peruensis, a main vector of Leishmania (Viannia) peruviana in the Peruvian Andes.
   Acta Trop. 2013 May;126(2):156-63.
5. Ishimaru Y, Gomez EA, Zhang F, Martini-Robles L, Iwata H, Sakurai T, Katakura K, Hashiguchi Y, Kato H.
   Dimiconin, a novel coagulation inhibitor from the kissing bug, Triatoma dimidiata, a vector of Chagas disease.
   J Exp Biol. 2012 Oct 15;215(Pt 20):3597-602.
6. Terada Y, Shiozaki Y, Shimoda H, Mahmoud HY, Noguchi K, Nagao Y, Shimojima M, Iwata H, Mizuno T, Okuda M, Morimoto M, Hayashi T, Tanaka Y, Mochizuki M, Maeda K.
   Feline infectious peritonitis virus with a large deletion in the 5'-terminal region of the spike gene retains its virulence for cats.
   J Gen Virol. 2012 Sep;93(Pt 9):1930-4.
7. Dong J, Zhu W, Saito A, Goto Y, Iwata H, Haga T.
   The E89K Mutation in the Matrix Protein of the Measles Virus Affects In Vitro Cell Death and Virus Replication Efficiency in Human PBMC.
   Open Virol J. 2012;6:68-72.
8. Kameyama M, Chuma T, Yokoi T, Yabata J, Tominaga K, Miyasako D, Iwata H, Okamoto K.
   Emergence of Salmonella enterica serovar infantis harboring IncI1 plasmid with bla(CTX-M-14) in a broiler farm in Japan.
   J Vet Med Sci. 2012 Sep;74(9):1213-6.
9. Fujita M, Kato H, Cáceres AG, Gomez EA, Velez L, Mimori T, Zhang F, Iwata H, Korenaga M, Sakurai T, Katakura K, Hashiguchi Y.
   Genotyping of sand fly species in Peruvian Andes where leishmaniasis is endemic.
   Acta Trop. 2012 Feb;121(2):93-8.
10. Kameyama M, Chuma T, Nishimoto T, Oniki H, Yanagitani Y, Kanetou R, Gotou K, Shahada F, Iwata H, Okamoto K.
    Effect of cooled and chlorinated chiller water on Campylobacter and coliform counts on broiler carcasses during chilling at a middle-size poultry processing plant.
    J Vet Med Sci. 2012 Jan;74(1):129-33.
11. Umeki S, Suzuki R, Shimojima M, Ema Y, Yanase T, Iwata H, Okuda M, Mizuno T.
    Characterization of monoclonal antibodies against canine P-selectin glycoprotein ligand-1 (PSGL-1).
    Vet Immunol Immunopathol. 2011 Jul 15;142(1-2):119-25.
12. Kato H, Gomez EA, Cáceres AG, Vargas F, Mimori T, Yamamoto K, Iwata H, Korenaga M, Velez L, Hashiguchi Y.
    Natural infections of man-biting sand flies by Leishmania and Trypanosoma species in the northern Peruvian Andes.
    Vector Borne Zoonotic Dis. 2011 May;11(5):515-21.
13. Kato H, Cáceres AG, Mimori T, Ishimaru Y, Sayed AS, Fujita M, Iwata H, Uezato H, Velez LN, Gomez EA, Hashiguchi Y.
    Use of FTA cards for direct sampling of patients' lesions in the ecological study of cutaneous leishmaniasis.
    J Clin Microbiol. 2010 Oct;48(10):3661-5.
14. Shimoda H, Ohno Y, Mochizuki M, Iwata H, Okuda M, Maeda K.
    Dogs as sentinels for human infection with Japanese encephalitis virus.
    Emerg Infect Dis. 2010 Jul;16(7):1137-9.
15. Kato H, Jochim RC, Gomez EA, Sakoda R, Iwata H, Valenzuela JG, Hashiguchi Y.
    A repertoire of the dominant transcripts from the salivary glands of the blood-sucking bug, Triatoma dimidiata, a vector of Chagas disease.
    Infect Genet Evol. 2010 Mar;10(2):184-91.
16. Kato H, Uezato H, Sato H, Bhutto AM, Soomro FR, Baloch JH, Iwata H, Hashiguchi Y.
    Natural infection of the sand fly Phlebotomus kazeruni by Trypanosoma species in Pakistan.
    Parasit Vectors. 2010 Feb 25;3:10.
17. Hamasaki R, Kato H, Terayama Y, Iwata H, Valenzuela JG.
    Functional characterization of a salivary apyrase from the sand fly, Phlebotomus duboscqi, a vector of Leishmania major.
    J Insect Physiol. 2009 Nov;55(11):1044-9.
18. Kuwahara K, Kato H, Gomez EA, Uezato H, Mimori T, Yamamoto Y, Calvopiña M, Cáceres AG, Iwata H, Hashiguchi Y.
    Genetic diversity of ribosomal RNA internal transcribed spacer sequences in Lutzomyia species from areas endemic for New World cutaneous leishmaniasis
    Acta Trop. 2009 Nov;112(2):131-6.
19. Dong JB, Saito A, Mine Y, Sakuraba Y, Nibe K, Goto Y, Komase K, Nakayama T, Miyata H, Iwata H, Haga T.
    Adaptation of wild-type measles virus to cotton rat lung cells: E89K mutation in matrix protein contributes to its fitness.
    Virus Genes. 2009 Dec;39(3):330-4
20. Iwamoto E, Wada Y, Fujisaki Y, Umeki S, Jones MY, Mizuno T, Itamoto K, Maeda K, Iwata H, Okuda M.
    Nationwide survey of leptospira antibodies in dogs in Japan: results from microscopic agglutination test and enzyme-linked immunosorbent assay.
    J Vet Med Sci. 2009 Sep;71(9):1191-9.
21. Nakagawa-Okamoto R, Arita-Nishida T, Toda S, Kato H, Iwata H, Akiyama M, Nishio O, Kimura H, Noda M, Takeda N, Oka T.
    Detection of multiple sapovirus genotypes and genogroups in oyster-associated outbreaks.
    Jpn J Infect Dis. 2009 Jan;62(1):63-6.
22. Huang L, Adachi T, Shimizu Y, Goto Y, Toyama J, Tanaka H, Akashi R, Sawaguchi A, Iwata H, Haga T.
    Characterization of lectin isolated from Momordica charantia seed as a B cell activator.
    Immunol Lett. 2008 Dec 22;121(2):148-56.
23. Kato H, Cáceres AG, Gomez EA, Mimori T, Uezato H, Marco JD, Barroso PA, Iwata H, Hashiguchi Y.
    Molecular mass screening to incriminate sand fly vectors of Andean-type cutaneous leishmaniasis in Ecuador and Peru.
    Am J Trop Med Hyg. 2008 Nov;79(5):719-21.
24. Terayama Y, Kato H, Gomez EA, Uezato H, Calvopiña M, Iwata H, Hashiguchi Y.
    Molecular typing of sand fly species (Diptera, Psychodidae, Phlebotominae) from areas endemic for Leishmaniasis in Ecuador by PCR-RFLP of 18S ribosomal RNA gene.
    J Vet Med Sci. 2008 Sep;70(9):907-13.
25. Kato H, Gomez EA, Yamamoto Y, Calvopiña M, Guevara AG, Marco JD, Barroso PA, Iwata H, Hashiguchi Y.
    Natural infection of Lutzomyia tortura with Leishmania (Viannia) naiffi in an Amazonian area of Ecuador.
    Am J Trop Med Hyg. 2008 Sep;79(3):438-40.
26. Tarama R, Kato H, Ishikawa Y, Miyaura H, Takeyoshi M, Iwata H.
    Gene expression changes induced by type IV allergy-inducible chemicals in dendritic cells.
    J Vet Med Sci. 2008 Jul;70(7):673-80.
27. Shiba N, Maeda K, Kato H, Mochizuki M, Iwata H.
    Differentiation of feline coronavirus type I and II infections by virus neutralization test.
    Vet Microbiol. 2007 Oct 6;124(3-4):348-52.
28. Kato H, Uezato H, Gomez EA, Terayama Y, Calvopiña M, Iwata H, Hashiguchi Y.
    Establishment of a mass screening method of sand fly vectors for Leishmania infection by molecular biological methods.
    Am J Trop Med Hyg. 2007 Aug;77(2):324-9.
29. Nishida T, Nishio O, Kato M, Chuma T, Kato H, Iwata H, Kimura H.
    Genotyping and quantitation of noroviruses in oysters from two distinct sea areas in Japan.
    Microbiol Immunol. 2007;51(2):177-84.
30. Adachi S, Hashimoto T, Takeyoshi M, Kato H, Iwata H.
    Development of a monoclonal antibody-based sandwich ELISA for detection of guinea pig interleukin-2.
    J Vet Med Sci. 2006 Dec;68(12):1281-7.
31. Ishikura Y, Kato H, Hashimoto T, Nishimura Y, Iwata H.
    Production and characterization of monoclonal antibodies against porcine interleukin-4.
    J Vet Med Sci. 2005 May;67(5):503-8.
32. Okuda M, Sakai Y, Matsuuchi M, Oikawa T, Watanabe M, Itamoto K, Iwata H, Kano R, Hasegawa A, Onishi T, Inokuma H.
    Enzyme-linked immunosorbent assay for the detection of canine Leptospira antibodies using recombinant OmpL1 protein.
    J Vet Med Sci. 2005 Mar;67(3):249-54.
33. Kato H, Uezato H, Katakura K, Calvopiña M, Marco JD, Barroso PA, Gomez EA, Mimori T, Korenaga M, Iwata H, Nonaka S, Hashiguchi Y.
    Detection and identification of Leishmania species within naturally infected sand flies in the andean areas of ecuador by a polymerase chain reaction.
    Am J Trop Med Hyg. 2005 Jan;72(1):87-93.
34. Watanabe R, Hasegawa A, Miyazawa T, Kato H, Iwata H.
    Generation of monoclonal antibodies to porcine interleukin 6 (PIL-6) using the recombinant PIL-6 expressed in Escherichia coli.
    J Vet Med Sci. 2004 Sep;66(9):1053-7.
35. Maeda K, Mizukoshi F, Hamano M, Kai K, Iwata H, Kondo T, Matsumura T.
    Development of an equine herpesvirus type 4-specific enzyme-linked immunosorbent assay using a B-cell epitope as an antigen.
    J Clin Microbiol. 2004 Mar;42(3):1095-8.
36. Miki R, Okuda M, Oikawa T, Watanabe M, Ma Z, Matsumoto K, Iwata H, Inokuma H.
    Centrosome amplification and chromosomal instability in feline lymphoma cell lines.
    J Vet Med Sci. 2004 Jul;66(7):797-805.
37. Utsumi T, Nakano K, Funakoshi T, Kayano Y, Nakao S, Sakurai N, Iwata H, Ishisaka R.
    Vertical-scanning mutagenesis of amino acids in a model N-myristoylation motif reveals the major amino-terminal sequence requirements for protein N-myristoylation.
    Eur J Biochem. 2004 Feb;271(4):863-74.
38. Mizukoshi F, Maeda K, Hamano M, Iwata H, Matsumura T, Kondo T, Sugiura T.
    IgG antibody subclass response against equine herpesvirus type 4 in horses.
    Vet Immunol Immunopathol. 2002 Sep 6;88(1-2):97-101.
39. Hayashi T, Maeda K, Hasegawa K, Nakai S, Hamachi T, Iwata H.
    Systemic administration of interferon-gamma-expressing plasmid reduces late allergic bronchitis in a mouse model of asthma.
    Int J Exp Pathol. 2002 Apr;83(2):81-6.
40. Morimoto M, Ohji T, Iwata H, Hayashi T.
    Lactic dehydrogenase virus (LDV) infection inhibits allergic eosinophil reaction in the airway.
    Res Vet Sci. 2002 Apr;72(2):131-6.
41. Hayashi T, Anayama H, Hasegawa K, Iwata H, Onodera T.
    Systemic administration of histamine reduces reovirus type 2-induced insulitis in suckling DBA/1 mice.
    J Comp Pathol. 2002 Feb-Apr;126(2-3):153-60.
42. Hayashi T, Morimoto M, Iwata H, Onodera T.
    Possible involvement of IL-12 in reovirus type-2-induced diabetes in newborn DBA/1 mice.
    Scand J Immunol. 2001 Jun;53(6):572-8.
43. Utsumi T, Sato M, Nakano K, Takemura D, Iwata H, Ishisaka R.
    Amino acid residue penultimate to the amino-terminal gly residue strongly affects two cotranslational protein modifications, N-myristoylation and N-acetylation.
    J Biol Chem. 2001 Mar 30;276(13):10505-13.
44. Iwata H, Manabe S, Yoshida A, Pereira EM, Inoue T.
    The complete nucleotide sequences of L3 and S7 segments of Ibaraki virus encoding for the major inner capsid proteins, VP3 and VP7.
    J Vet Med Sci. 2001 Jan;63(1):73-8.
45. Iwata H, Yamamoto M, Hasegawa A, Kurata K, Inoue T.
    Expression of porcine interleukin-2 in Escherichia coli.
    J Vet Med Sci. 2000 Oct;62(10):1101-4.
46. Iwata H, Murase K, Inoue T.
    Monoclonal antibody against bovine alpha1-acid glycoprotein.
    J Vet Med Sci. 2000 Oct;62(10):1099-100.
47. Nara Pereira EM, Iwata H, Inoue T.
    The complete nucleotide sequence of segment L2 of Ibaraki virus encoding for the antigen recognized by neutralizing antibodies.
    J Vet Med Sci. 2000 Mar;62(3):317-21.
48. Nara Pereira EM, Nishida T, Tokunaga R, Iwata H, Inoue T.
    Cloning and expression of the M5 RNA segment encoding outer capsid VP5 of epizootic hemorrhagic disease virus Japan serotype 2, Ibaraki virus.
    J Vet Med Sci. 2000 Mar;62(3):301-4.
49. Morimoto M, Iwata H, Hayashi T.
    Lactic dehydrogenase virus infection inhibits allergic eosinophil reaction and IL-5 gene expression in vivo.
    Int Arch Allergy Immunol. 1999 Sep;120(1):78-84.
50. Ohno K, Terado M, Iwata H, Inokuma H, Onishi T.
    Expression of recombinant feline serum amyloid A (SAA) protein.
    J Vet Med Sci. 1999 Aug;61(8):915-20.
51. Ishisaka R, Sato N, Tanaka K, Takeshige T, Iwata H, Klostergaard J, Utsumi T.
    A part of the transmembrane domain of pro-TNF can function as a cleavable signal sequence that generates a biologically active secretory form of TNF.
    J Biochem. 1999 Aug;126(2):413-20.
52. Morimoto M, Iwata H, Hayashi T.
    Lactic dehydrogenase virus inhibits allergic immunoglobulin E production: in vivo molecular analysis of cytokines.
    Scand J Immunol. 1999 Aug;50(2):211-4.
53. Kashima T, Iwata H, Inoue T.
    Expression of bovine interleukin-2 in insect cells by recombinant baculovirus.
    J Vet Med Sci. 1999 Jun;61(6):705-7.
54. Ohno K, Matsumoto K, Nakaichi M, Iwata H, Morimoto M, Hayashi T, Inokuma H, Onishi T.
    A canine case of multiple IgA myeloma
    Nihon Juigaku Zasshi. 1999 May;52(5):315-318
55. Hayashi T, Iwata H, Onodera T.
    Role of interleukin-2 in pancreatic islet-cell destruction in reovirus type 2-infected DBA/1 suckling mice.
    J Comp Pathol. 1999 Apr;120(3):313-20.
56. Kashima T, Hasegawa A, Iwata H, Inoue T.
    Expression of Recombinant bovine L-selectin in Escherichia coli and insect cells.
    J Vet Med Sci. 1999 Mar;61(3):251-4.
57. Kashima T, Morishita A, Iwata H, Maeda K, Inoue T.
    Expression of bovine cytokines in Escherichia coli.
    J Vet Med Sci. 1999 Feb;61(2):171-3.
58. Hayashi T, Morimoto M, Iwata H, Onodera T.
    Interferon-gamma plays a role in pancreatic islet-cell destruction of reovirus type 2-induced diabetes-like syndrome in DBA/1 suckling mice.
    Int J Exp Pathol. 1998 Oct;79(5):313-20.
59. Takeyoshi M, Iwata H, Inoue T.
    Cloning and sequence of guinea pig interleukin 2 (IL-2).
    Arch Toxicol. 1998 Oct;72(10):676-8.
60. Yasunaga S, Maeda K, Matsumura T, Kai K, Iwata H, Inoue T.
    Diagnosis and sero-epizootiology of equine herpesvirus type 1 and type 4 infections in Japan using a type-specific ELISA.
    J Vet Med Sci. 1998 Oct;60(10):1133-7.
61. Utsumi T, Tou E, Takemura D, Ishisaka R, Yabuki M, Iwata H.
    Met-Gly-Cys motif from G-protein alpha subunit cannot direct palmitoylation when fused to heterologous protein.
    Arch Biochem Biophys. 1998 Jan 15;349(2):216-24.
62. Tanizaki H, Tanaka H, Iwata H, Kato A.
    Activation of macrophages by sulfated glycopeptides in ovomucin, yolk membrane, and chalazae in chicken eggs.
    Biosci Biotechnol Biochem. 1997 Nov;61(11):1883-9.
63. Takeyoshi M, Inoue T, Iwata H.
    Streptavidin-reactive protein in Fasciola hepatica.
    Vet Parasitol. 1995 Jun;58(3):255-61.
64. Iwata H, Hayashi T.
    Interleukin-6 production by macrophages from BALB/c mice with a chronic infection of lactic dehydrogenase virus.
    Jikken Dobutsu. 1994 Oct;43(4):559-62.
65. Takeyoshi M, Inoue T, Iwata H.
    IgE responses to Fasciola hepatica extract in several inbred mouse strains.
    Jikken Dobutsu. 1994 Jul;43(3):449-51.
66. Martinez-Torrecuadrada JL, Iwata H, Venteo A, Casal I, Roy P.
    Expression and characterization of the two outer capsid proteins of African horsesickness virus: the role of VP2 in virus neutralization.
    Virology. 1994 Jul;202(1):348-59.
67. Abe F, Hayashi T, Iwata H, Inoue T.
    Effect of partial hepatectomy on lactic dehydrogenase-5 clearance in mice.
    J Vet Med Sci. 1994 Jun;56(3):563-4.
68. Inoue T, Nakakouji M, Iwata H.
    Delayed-type hypersensitivity in mice experimentally infected with Fusobacterium necrophorum.
    J Vet Med Sci. 1994 Feb;56(1):59-63.
69. Iwata H, Ueda T, Takayanagi K, Wada M, Inoue T.
    Swine interleukin 2 activity produced by mesenteric lymph node cells.
    Vet Med Sci. 1993 Oct;55(5):729-34.
70. Iwata H, Inoue T.
    The colorimetric assay for swine lymphocyte blastogenesis.
    J Vet Med Sci. 1993 Aug;55(4):697-8.
71. Wu X, Chen SY, Iwata H, Compans RW, Roy P.
    Multiple glycoproteins synthesized by the smallest RNA segment (S10) of bluetongue virus.
    J Virol. 1992 Dec;66(12):7104-12.
72. Iwata H, Yamagawa M, Roy P.
    Evolutionary relationships among the gnat-transmitted orbiviruses that cause African horse sickness, bluetongue, and epizootic hemorrhagic disease as evidenced by their capsid protein sequences.
    Virology. 1992 Nov;191(1):251-61.
73. Iwata H, Chuma T, Roy P.
    Characterization of the genes encoding two of the major capsid proteins of epizootic haemorrhagic disease virus indicates a close genetic relationship to bluetongue virus.
    J Gen Virol. 1992 Apr;73 ( Pt 4):915-24.
74. Iwata H, Hirasawa T, Roy P.
    Complete nucleotide sequence of segment 5 of epizootic haemorrhagic disease virus; the outer capsid protein VP5 is homologous to the VP5 protein of bluetongue virus.
    Virus Res. 1991 Aug;20(3):273-81.
75. Hayashi T, Iwata H, Hasegawa T, Ozaki M, Yamamoto H, Onodera T.
    Decrease in neutrophil migration induced by endotoxin and suppression of interleukin-1 production by macrophages in lactic dehydrogenase virus-infected mice.
    J Comp Pathol. 1991 Feb;104(2):161-70.
76. Iwata H, Inoue T, Ono K, Hasegawa A, Tomoda I.
    The microheterogeneity of bovine serum alpha 1-acid glycoprotein.
    Nihon Juigaku Zasshi. 1989 Aug;51(4):717-21.
77. Inoue T, Iwata H, Matsumura K, Goto N.
    Acid alpha-naphthyl acetate esterase (ANAE) staining of porcine lymphocytes.
    Nihon Juigaku Zasshi. 1988 Dec;50(6):1169-76.
78. Iwata H, Ono K, Hasegawa A, Tomoda I.
    Serum alpha 1-acid glycoprotein levels in cows.
    Nihon Juigaku Zasshi. 1988 Oct;50(5):1119-20. 
79. Iwata H, Ono K, Hasegawa A, Tomoda I.
    Alpha 1-acid glycoprotein in bovine lymphocytes.
    Nihon Juigaku Zasshi. 1988 Oct;50(5):996-1002.
80. Yoshikawa K, Hirota Y, Goitsuka R, Iwata H, Yasuda K, Hayashi T, Ono K, Sasaki N, Hasegawa A, Tomoda I.
    Pulmonary infiltrates with eosinophilia syndrome in a dog.
    Nihon Juigaku Zasshi. 1987 Dec;49(6):1160-1.
81. Iwata H, Ono K, Hasegawa A, Tomoda I.
    Isolation of bovine serum alpha 1-acid glycoprotein.
    Nihon Juigaku Zasshi. 1987 Apr;49(2):383-6.
82. Ono K, Yasuda K, Iwata H, Nakayama H, Hasegawa A, Tomoda I.
    Fluorescein angiogram in diabetic dogs.
    Nihon Juigaku Zasshi. 1986 Dec;48(6):1257-61.
83. Iwata H, Yasuda K, Ono K, Hasegawa A, Tomoda I.
    A lactate dehydrogenase anomaly in a cat.
    Nihon Juigaku Zasshi. 1986 Feb;48(1):145-8.

著書

1. 獣医衛生学（3-3 疾病制御）
   文永堂出版 2005
2. 獣医公衆衛生学 第3版（Ⅱ-2 疾病および健康障害の発生 要因，Ⅳ-4-11(1)異物と衛生動物）
   文永堂出版 2004
3. 概説 家畜感染症学（各論Ⅱ 豚伝染性疾病）
   九州大学出版会 2000
4. 家畜衛生学（疾病予防，解説2 監視伝染病）
   文永堂出版 2000
5. イラストでみる猫の病気（５. 消化器の病気、10. 黄疸）
   講談社サイエンティフィック 1998
6. 新獣医内科学（第6章 物理的原因による疾病）
   文永堂出版 1997

論文発表（2015年以前、渋谷准教授）

原著論文

1. Zielke N, Kim KJ, Tran V, Shibutani ST, Bravo MJ, Nagarajan S, van Straaten M, Woods B, von Dassow G, Rottig C, Lehner CF, Grewal SS, Duronio RJ, Edgar BA.
   Control of Drosophila endocycles by E2F and CRL4(CDT2).
   Nature. 2011; 480(7375): 123-127.
2. Tanaka KA, Suzuki KG, Shirai YM, Shibutani ST, Miyahara MS, Tsuboi H, Yahara M, Yoshimura A, Mayor S, Fujiwara TK, Kusumi A.
   Membrane molecules mobile even after chemical fixation.
   Nature Methods. 2010; 7(11): 865-866.
3. Shibutani ST, de la Cruz AF, Tran V, Turbyfill WJ 3rd, Reis T, Edgar BA, Duronio RJ.
   Intrinsic negative cell cycle regulation provided by PIP box- and Cul4Cdt2-mediated destruction of E2f1 during S phase.
   Developmental Cell. 2008; 15(6): 890-900.
4. Shibutani S, Swanhart LM, Duronio RJ.
   Rbf1-independent termination of E2f1-target gene expression during early Drosophila embryogenesis.
   Development. 2007; 134(3): 467-478.

総説論文

1. Shibutani ST, Saitoh T, Nowag H, Münz C, Yoshimori T.
   Autophagy and autophagy-related proteins in the immune system.
   Nature Immunology. 2015; 16(10): 1014-1024.
   
2. Shibutani ST, Yoshimori T.
   Autophagosome formation in response to intracellular bacterial invasion.
   Cellular Microbiology. 2014; 16(11): 1619-1626.
3. Shibutani ST, Yoshimori T.
   A current perspective of autophagosome biogenesis.
   Cell Research. 2014; 24(1): 58-68.
4. Hamasaki M^✝, Shibutani ST^✝, Yoshimori T.
   Up-to-date membrane biogenesis in the autophagosome formation.
   Current Opinion in Cell Biology. 2013; 25(4): 455-460. (^✝Equal Contribution)
5. 渋谷周作、齊藤達哉、吉森保
   オートファジーと生体防御応答.
   実験医学増刊「Theオートファジー」. 2017; 35(15), 2602-2608
6. 渋谷周作、吉森保
   選択的オートファジー：メカニズムと膜の起源.
   日本膜学会雑誌．2015; 40(1): 9-20
7. 渋谷周作、吉森保
   オートファジーによる細菌排除.
   Surgery Frontier．2015; 22(1), 66-68
8. 渋谷周作、吉森保
   オートファジー．
   医学のあゆみ．2014; 249(5):375．
9. 渋谷周作、吉森保
   オートファジーにおける膜の起源．
   生体の科学．2012; 63(5): 478-481．